Histonedeacetylase inhibitor eluting medical device

摘要

A medical device comprising an implantable structure; and a histone deacetylase inhibitor, in therapeutic dosages. The histone deacetylase inhibitor is releasably affixed to the implantable structure for the treatment of restenosis following vascular injury. The device may further comprise an anti-proliferative, in therapeutic dosages, releasably affixed to the implantable structure for the treatment of restenosis following vascular injury. The histone deacetylase inhibitor may comprise trichostatin A. The anti-proliferative may comprise rapamycin. <IMAGE>