| 摘要 |
A gastrointestinal device for implanting within a pylorus, a duodenal bulb, and a duodenum of a patient's gastrointestinal tract includes an expandable structure includes a proximal portion having a plurality of spring arms and a distal portion having a plurality of spring arms, the proximal and distal portions coupled by a rigid central cylinder having a diameter capable of fitting within the pylorus and having a length greater than a width of the pylorus. A membrane is coupled to and covering at least a portion of one of the proximal portion and the distal portion of the expandable structure. An intestinal bypass sleeve is coupled to at least one of the proximal and distal portions of the expandable structure and having a length sufficient to extend at least partially into the duodenum. In the expanded configuration, the proximal portion has a diameter larger than a maximum opening diameter of the pylorus and further wherein, in the expanded configuration, the distal portion has a diameter larger than a maximum opening diameter of the pylorus. |
| 主权项 |
1. A gastrointestinal device for implanting within a pylorus, a duodenal bulb, and a duodenum of a patient's gastrointestinal tract, the device having a central axis and configured to have an expanded configuration and a contracted configuration, the device comprising:
a proximal expandable structure including an inner proximal portion near the central axis and an outer proximal portion extending radially outward from the central axis and configured for engaging a first wall of the pylorus at a first location adjacent the pyloric antrum, the outer proximal portion extending distally such that, upon implantation, in the expanded configuration, the inner proximal portion is configured to minimize a compressive force exerted to the pylorus; a distal expandable structure including an inner distal portion near the central axis and an outer distal portion extending radially outward from the central axis and configured for engaging a second wall of the pylorus at a second location adjacent the duodenal bulb, the outer distal portion extending proximally such that, upon implantation, in the expanded configuration, the inner distal portion is configured to minimize a compressive force exerted to the pylorus; and a central cylinder portion coupling the proximal expandable structure and the distal expandable structure and having a diameter that is equal to or larger than a maximum diameter of the pylorus such that the central cylinder portion does not restrict flow through the pylorus; wherein in the expanded configuration, the proximal expandable structure and distal expandable structure each have a diameter larger than a maximum opening diameter of the pylorus. |
