| 发明名称 |
PHARMACEUTICAL COMPOSITIONS |
| 摘要 |
PROBLEM TO BE SOLVED: To provide methods and compositions which comprise effective amounts of analgesics to treat a subject, including reducing or eliminating an adverse effect associated with the analgesics.SOLUTION: A bilayer tablet composition has an immediate-release layer and a controlled-release layer containing (1) effective amounts of (a) an opioid analgesic such as hydrocodone, oxycodone and morphine, (b) a stimulant such as aminophylline, caffeine and dyphylline, and (c) an antiemetic such as aprepitant, dronabinol and perphenazine, and (2) a pharmaceutically acceptable carrier or vehicle.SELECTED DRAWING: None |
| 申请公布号 |
JP2016155847(A) |
申请公布日期 |
2016.09.01 |
| 申请号 |
JP20160074147 |
申请日期 |
2016.04.01 |
| 申请人 |
CHARLESTON LABORATORIES INC |
发明人 |
PAUL BOSSE;AMELING JOHN;BERNARD SCHACHTEL;RAY TAKIGIKU |
| 分类号 |
A61K45/06;A61K9/14;A61K9/20;A61K9/24;A61K9/48;A61K31/13;A61K31/135;A61K31/138;A61K31/165;A61K31/167;A61K31/192;A61K31/195;A61K31/355;A61K31/365;A61K31/381;A61K31/403;A61K31/404;A61K31/4045;A61K31/415;A61K31/4168;A61K31/4196;A61K31/42;A61K31/422;A61K31/4402;A61K31/454;A61K31/4545;A61K31/46;A61K31/485;A61K31/515;A61K31/52;A61K31/522;A61K31/5415;A61K31/55;A61K31/63;A61K47/02;A61K47/12;A61K47/32;A61K47/38;A61P25/04;A61P25/06;A61P39/00;A61P43/00 |
主分类号 |
A61K45/06 |
| 代理机构 |
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