A method of treatment for patients with vascular occlusion and thromboembolic disorders including the acquired disease state of thrombotic stroke, by administering activated protein C. The administration of aPC provides a highly selective therapeutic agent with a low potential for causing bleeding complications. The administration of aPC is beneficial in preventing the local extension of the microvascular and macrovascular occluding arterial thrombus, thereby reducing the neurological deficit resulting from the stroke.
申请公布号
WO9842358(A1)
申请公布日期
1998.10.01
申请号
WO1998US05732
申请日期
1998.03.24
申请人
ELI LILLY AND COMPANY;GRINNELL, BRIAN, W.;HOWEY, DANIEL, C.;JACKSON, CHARLES, V.
发明人
GRINNELL, BRIAN, W.;HOWEY, DANIEL, C.;JACKSON, CHARLES, V.