CELL-PENETRATING PEPTIDE AND CONJUGATE COMPRISING SAME

摘要

The present invention relates to a cell-penetrating peptide derived from telomerase, a conjugate of the cell-penetrating peptide with an anticancer agent, and a composition comprising the conjugate. An effective means for transferring a cancer-specific anticancer agent can be provided by using the cell-penetrating peptide according to the present invention. More particularly, by preparing the conjugate of the present invention wherein the cell-penetrating peptide and the anticancer agent are combined, the application concentration of a conventional anticancer agent can be reduced and cancer specificity can be provided, and thus an effect of reducing side effects during the treatment process can be obtained.

主权项

1. A cell penetrating carrier peptide derived from telomerase, wherein the peptide is the peptide comprising amino acid sequence of SEQ ID NO 1, the peptide having above 80% homology with the above-mentioned peptide sequences, or the fragment of the above mentioned thereof.