Acid-solubilized copper-ammonium complexes and copper-zinc-ammonium complexes, compositions, preparations, methods, and uses

摘要

An antimicrobial composition is disclosed that contains an acid-solubilized copper ammonium or copper-zinc ammonium complex that is effective against microorganisms such as nosocomial or environmental bacteria, fungi, viruses, and the like. The antimicrobial composition can be used in the preparation of a medicament for treating microbes or a microbial infection, and may contain a carrier to create a cream, soap, wash, spray, dressing, cleanser, cosmetic product, topical drug product, or other antimicrobial product.

主权项

1. An antimicrobial soluble copper composition comprising:
a solution comprising 10-160 grams/liter hydrated copper sulfate; a basic ammonium salt added to the hydrated copper sulfate solution at 15-60 grams/liter to generate an insoluble copper-ammonium complex; and at least one water soluble acid selected from the group consisting of phosphorous acid and phosphoric acid added to the hydrated copper sulfate solution to solubilize the copper-ammonium complex and to control the pH of the clear blue acid-solubilized copper-ammonium solution thus formed; wherein when present the amount of phosphorous acid is 24-80 grams/liter and wherein when present the amount of phosphoric acid is 17-85 grams/liter; the resulting composition having synergistic antimicrobial properties greater than the antimicrobial properties of each constituent component.