发明名称 |
Mono- und Diacylderivate von LL-F28249-Verbindungen. |
摘要 |
The present invention relates to novel 5-acyl, 23-acyl and 5,23-diacyl derivatives of the LL-F28249 compounds. These LL-F28249 compounds (collectively) are isolates from the fermentation broth of Streptomyces cyaneogriseus subspecies noncyanogenus having deposit accession number NRRL 15773. The present 5-acyl and 5,23-diacyl compounds are prepared by selective acylation using acid chlorides or anhydrides in the presence of 4-dimethylaminopyridine. The 23-acyl compounds are prepared by selective acylation of the 5-O-silylated LL-F28249 compounds. These novel compounds have potent anthelmintic, insecticidal, ectoparasiticidal, nematicidal and acaricidal activity. Compositions containing these derivatives of LL-F28249 also are described herein. |
申请公布号 |
DE3787942(T2) |
申请公布日期 |
1994.05.11 |
申请号 |
DE19873787942T |
申请日期 |
1987.08.25 |
申请人 |
AMERICAN CYANAMID CO., STAMFORD, CONN., US |
发明人 |
ASATO, GORO, TITUSVILLE NEW JERSEY 08560, US |
分类号 |
C07D493/22;A01N43/90;A01N49/00;A23K20/195;A61K31/365;A61P33/00;C07H19/01 |
主分类号 |
C07D493/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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