HUMAN Prt1-LIKE SUBUNIT PROTEIN (hPrt1) AND HUMAN eIF4G-LIKE PROTEIN (p97) GENES
摘要
The present invention relates to novel human Prt1 (hPrt1) and eIF4G-like (p97) proteins which are involved in eukaryotic transcription. In particular, isolated nucleic acid molecules are provided encoding the human hPrt1 and p97 proteins. hPrt1 and p97 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of hPrt1 and p97 activity. Also provided are therapeutic methods for treating disease states associated with the hPrt1 and p97 proteins.
申请公布号
WO9825957(A2)
申请公布日期
1998.06.18
申请号
WO1997US22664
申请日期
1997.12.12
申请人
HUMAN GENOME SCIENCES, INC.;MCGILL UNIVERSITY;OLSEN, HENRIK, S.;RUBEN, STEVEN, M.;SONENBERG, NAHUM;IMATAKA, HIROAKI;METHOT, NATHALIE;ROM, ERAN
发明人
OLSEN, HENRIK, S.;RUBEN, STEVEN, M.;SONENBERG, NAHUM;IMATAKA, HIROAKI;METHOT, NATHALIE;ROM, ERAN