Method for analyzing a polynucleotide containing a variable sequence

摘要

PCT No. PCT/GB96/00848 Sec. 371 Date Oct. 6, 1997 Sec. 102(e) Date Oct. 6, 1997 PCT Filed Apr. 9, 1996 PCT Pub. No. WO96/31622 PCT Pub. Date Oct. 10, 1996A method of analyzing a polynucleotide target involves incubating the target with an oligonucleotide probe, generally an array of immobilised oligonucleotide probes, to form a duplex, and using ligase or polymerase to extend one chain of the duplex. A point mutation or variable number tandem repeat section may be analysed. Arrays of immobilised oligonucleotides are provided for use in the method.