| 发明名称 |
2-DEOXY-SCYLLO-INOSOSE REDUCTASE |
| 摘要 |
[Problem] The purpose of the present invention is to produce (−)-vibo-quercitol with high efficiency by a simple process. Particularly, it is intended to utilize an enzyme capable of converting 2-deoxy-scyllo-inosose to (−)-vibo-quercitol directly.;[Solution] A 2-deoxy-scyllo-inosose reductase which is originated from a microorganism capable of utilizing (−)-vibo-quercitol and has the properties (a) to (c): (a) the enzyme has a catalytic activity of converting 2-deoxy-scyllo-inosose to (−)-vibo-quercitol; (b) the activity of the enzyme becomes maximum at a pH value of 7.0 to 9.0; and (c) a polypeptide moiety in the enzyme has a molecular mass of about 36 kDa as measured by SDS-polyacrylamide electrophoresis. |
| 申请公布号 |
US2016208224(A1) |
申请公布日期 |
2016.07.21 |
| 申请号 |
US201414914500 |
申请日期 |
2014.12.05 |
| 申请人 |
ASAHI KASEI CHEMICALS CORPORATION |
发明人 |
Konishi Kazunobu;Itoh Nobuya;Kurokawa Junji |
| 分类号 |
C12N9/04;C12P7/02 |
主分类号 |
C12N9/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. (1) A 2-deoxy-scyllo-inosose reductase having the following properties (a) through (c), derived from a microorganism having the ability to utilize (−)-vibo-quercitol:
(a) the enzyme has catalytic activity to convert 2-deoxy-scyllo-inosose into (−)-vibo-quercitol; (b) the enzyme presents maximum activity at pH 7.0-9.0; and (c) the molecular mass of a polypeptide moiety of the enzyme measured by SDS-polyacrylamide electrophoresis is 36 kDa. |
| 地址 |
Tokyo JP |
