发明名称 |
ENCAPSULATED SENSORS AND SENSING SYSTEMS FOR BIOASSAYS AND DIAGNOSTICS AND METHODS FOR MAKING AND USING THEM |
摘要 |
In alternative embodiments, the invention provides high throughput, multiplexed systems or methods for detecting a biological, a physiological or a pathological maker, or a single molecule or a single cell using a droplet microfluidics system integrated with use of a sensor or a sensing system, an aptamer, or a DNAzyme. In alternative embodiments, the sensor or sensing system comprises a nucleic acid based, an antibody based, an enzyme based or a chemical based sensor or sensing system. In alternative embodiments, the invention provides methods for detecting a biological, a physiological or a pathological marker, or a single molecule or a single cell using a droplet system integrated with rapid and sensitive fluorescence detection systems including, for example, a 3D Particle Detector. In alternative embodiments, the invention provides systems comprising Integrated Comprehensive Droplet Digitial Detection (IC 3D). |
申请公布号 |
EP3049067(A2) |
申请公布日期 |
2016.08.03 |
申请号 |
EP20140850080 |
申请日期 |
2014.09.24 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
ZHAO, WEIAN;KANG, DONG-KU;ZHANG, KAIXIANG;ALI, MD MONSUR;ECKERT, MARK A.;LI, FENG;GRATTON, ENRICO;DIGMAN, MICHELLE A.;LABANIEH, LOUAI;LU, MENGROU |
分类号 |
A61K9/127;C12M1/34;C12M3/00 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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