发明名称 |
NOVEL HIGH THROUGHPUT SCREENING METHOD OF DRUG FOR PHYSIOLOGICALLY ACTIVE PROTEIN |
摘要 |
The present invention is intended to provide a safe and quick means for screening a drug to a bioactive protein, in particular, an inhibitor, using a cell-free protein synthesis system with the use of a wheat embryo extract solution. The present inventors have strenuously studied to solve the matters above and finally completed the present invention by, in a system with the use of a wheat embryo, among cell-free protein synthesis means, constructing a synthesis system of a bioactive protein while sustaining its activities, and constructing a system for screening an inhibitor candidate to SARS 3CL pro , as an example using the synthesis system.
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申请公布号 |
EP1669759(A1) |
申请公布日期 |
2006.06.14 |
申请号 |
EP20040787754 |
申请日期 |
2004.09.08 |
申请人 |
CELLFREE SCIENCES CO., LTD. |
发明人 |
ENDO, YAETA;SAWASAKI, TATSUYA |
分类号 |
G01N33/50;C12N15/50;C12N15/57;C12P21/02;G01N33/569;(IPC1-7):G01N33/573;C12N9/50;C12P21/00;C12Q1/68 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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