发明名称 |
FUNCTIONAL CURE OF RETROVIRAL INFECTION |
摘要 |
The application relates to methods of curing retroviral infections, i.e. ensuring remission of retroviral infections, more particularly HIV infections, by administering a compound which is capable of binding to the LEDGF/p75 binding pocket of HIV-integrase and inhibiting LEDGF/p75-IN protein-protein interaction. The application further relates to the use of LEDGINs in retroviral gene therapy. |
申请公布号 |
WO2016180770(A1) |
申请公布日期 |
2016.11.17 |
申请号 |
WO2016EP60314 |
申请日期 |
2016.05.09 |
申请人 |
KATHOLIEKE UNIVERSITEIT LEUVEN |
发明人 |
CHRIST, Frauke;DEBYSER, Zeger;GIJSBERS, Rik;VRANCKX, Lenard |
分类号 |
A61K31/00 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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