发明名称 |
Core structure of gp41 from the HIV envelope glycoprotein |
摘要 |
Described are the crystal structure of the alpha -helical domain of the gp41 component of HIV-1 envelope glycoprotein which represents the core of fusion-active gp41, methods of identifying and designing drugs which inhibit gp41 function and drugs which do so.
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申请公布号 |
US6150088(A) |
申请公布日期 |
2000.11.21 |
申请号 |
US19980062241 |
申请日期 |
1998.04.17 |
申请人 |
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH |
发明人 |
CHAN, DAVID C.;FASS, DEBORAH;LU, MIN;BERGER, JAMES M.;KIM, PETER S. |
分类号 |
A61K38/00;C07K14/16;(IPC1-7):C12Q1/70;C12P21/06;C07K5/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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