摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide attenuated live cultures of pathogenic protozoan parasite, Neospora, and live vaccines against neosporosis prepared therefrom which are useful in the prevention of clinical disease and abortion in mammals. <P>SOLUTION: The live vaccine comprises a cultured product of cells of a strain derived from a pathogenic parent strain of a species of Neospora, which cells exhibit attenuated pathogenicity compared to those of the parent strain but which are capable of triggering an immune response that protects a mammal against neosporosis when administered as a live vaccine. <P>COPYRIGHT: (C)2005,JPO&NCIPI</p> |