| 发明名称 | Kinase inhibitor polymorphs | ||
| 摘要 | Polymorphs of chemical compounds that modulate kinase activity, including PI3K activity, and chemical compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3K activity, are described herein. | ||
| 申请公布号 | US9403820(B2) | 申请公布日期 | 2016.08.02 |
| 申请号 | US201214357144 | 申请日期 | 2012.11.12 |
| 申请人 | Intellikine LLC;Sigma-Aldrich Company Limited | 发明人 | Ren Pingda;Martin Michael;Worrall Christopher Peter;Gancedo Susanna del Rio |
| 分类号 | C07D471/04 | 主分类号 | C07D471/04 |
| 代理机构 | Honigman Miller Schwartz and Cohn LLP | 代理人 | Honigman Miller Schwartz and Cohn LLP ;Yang Lucy X.;O'Brien Jonathan P. |
| 主权项 | 1. A crystalline polymorph of an HCl salt of a compound of Formula I:wherein said crystalline polymorph is HCl Pattern 1 characterized by X-ray powder diffraction peaks at 9.2 (±0.4) degrees, 17.5 (±0.4) degrees, 24.5 (±0.4) degrees, 27.4 (±0.4) degrees, and 28.2 (±0.4) degrees two theta. | ||
| 地址 | La Jolla CA US | ||