发明名称 |
CHLAMYDIA-ACTIVATED B CELL PLATFORMS AND METHODS THEREOF |
摘要 |
Disclosed herein is a Chlamydia-activated B cell (CAB) platform. Also disclosed is a method of enhancing a population of B cells, comprising exposing said B cells to Chlamydia spp. under conditions suitable to enhance the population of B cells, such that expansion and differentiation of said B cells takes place, and said B cells are exposed or crosslinked to an antigen. Also disclosed are methods of producing said CABs, and treating a subject in need thereof with said CABs. |
申请公布号 |
WO2016130667(A1) |
申请公布日期 |
2016.08.18 |
申请号 |
WO2016US17338 |
申请日期 |
2016.02.10 |
申请人 |
OHIO STATE INNOVATION FOUNDATION |
发明人 |
CHERPES, Thomas;MIGUEL, Rodolfo Vicetti |
分类号 |
A61P37/04;A61K39/118;C12N5/0781 |
主分类号 |
A61P37/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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