DIAGNOSTIC ASSAY USING PARTICLES WITH MAGNETIC PROPERTIES

摘要

A novel system for the analysis of molecules and cells, comprising clusters where a non-magnetic particle is supplemented with magnetic particles to form a characteristic pattern, fingerprint or bar code. Methods and devices for formation of such particles are also disclosed.

主权项

1. A particle comprising a non-magnetic porous particle having an exterior surface, pores and an interior surface defined by said pores, the porous particle comprising at least one polymer, said particle having at least one magnetic particle covalently bound to the outer parts thereof, wherein the smallest diameter of at least 95 percent per weight of all magnetic particles is larger than the largest diameter of at least 95% of the pores of the porous particles, wherein a fraction of the magnetic particles have a diameter such that they enter the non-magnetic porous particle, and wherein said at least one magnetic particle constitutes a feature capable of distinguishing one group of particles from another.