发明名称 |
PHOTOMETRIC ENTHALPY CHANGE DETECTION SYSTEM AND METHOD |
摘要 |
A method for detecting an enthalpy change includes providing a first mixture and a second mixture to a drop generator. The first mixture includes a ligand. The second mixture contains a target molecule. The method further includes generating a drop in the drop generator. The drop includes the target molecule, a temperature-sensitive reporter compound, and the ligand. The method also includes measuring a property of the temperature-sensitive reporter compound in the drop to determine an amount of enthalpy change that has occurred. |
申请公布号 |
US2016187273(A1) |
申请公布日期 |
2016.06.30 |
申请号 |
US201414583239 |
申请日期 |
2014.12.26 |
申请人 |
Palo Alto Research Center Incorporated |
发明人 |
Recht Michael I.;Martini Joerg;Whiting Gregory L.;Torres Francisco E. |
分类号 |
G01N25/48 |
主分类号 |
G01N25/48 |
代理机构 |
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代理人 |
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主权项 |
1. A method for performing calorimetry comprising:
providing a first mixture in a first fluid comprising a ligand to a drop generator; providing a second mixture in the first fluid comprising a target molecule to the drop generator; generating a drop in a second fluid, wherein the first fluid and the second fluid are immiscible, the drop comprising the target molecule, a temperature-sensitive reporter compound, and the ligand; and measuring the temperature of the drop over time to perform calorimetry. |
地址 |
Palo Alto CA US |