发明名称 |
VACCINE COMPRISING STREPTOCOCCUS PNEUMONIAE CAPSULAR POLYSACCHARIDE CONJUGATES |
摘要 |
The present invention discloses an immunogenic composition comprising S. pneumoniae capsular saccharide conjugates from serotypes 19A and 19F wherein 19A is conjugated to a first bacterial toxoid and 19F is conjugated to a second bacterial toxoid. Vaccines, methods of making vaccines and uses of the vaccines are also described. |
申请公布号 |
US2016243219(A1) |
申请公布日期 |
2016.08.25 |
申请号 |
US201614987770 |
申请日期 |
2016.01.05 |
申请人 |
GLAXOSMITHKLINE BIOLOGICALS S.A. |
发明人 |
BIEMANS Ralph Leon;GARCON Nathalie Marie-Josephe;HERMAND Philippe Vincent;POOLMAN Jan;VAN MECHELEN Marcelle Paulette |
分类号 |
A61K39/385;A61K47/48;A61K39/09 |
主分类号 |
A61K39/385 |
代理机构 |
|
代理人 |
|
主权项 |
1. An immunogenic composition comprising S. pneumoniae capsular saccharide conjugates from serotypes 19A and 19F wherein 19A is conjugated to a first bacterial toxoid comprising pneumolysin detoxified by chemical means or diphtheria toxoid or CRM197 and 19F is conjugated to a second bacterial toxoid comprising diphtheria toxoid or CRM197 and further comprising conjugates of S. pneumoniae capsular saccharides 1, 4, 5, 6B, 7F, 9V, 14, 18C, 22F and 23F. |
地址 |
RIXENSART BE |