System and method for ophthalmic surface measurements based on objective quality estimation

摘要

Systems and methods for measuring a topography of an optical tissue surface of an eye are provided by combining a measured elevation of the surface with a priori information of the surface to provide an estimate of mean and covariance of post-measurement orthogonal polynomial sequence amplitudes associated with the surface, determining a variance of elevation of the surface from the estimate, and constructing the topography from the estimate of mean and covariance of post-measurement amplitudes based on a comparison of the variance of elevation of the surface with a pre-determined threshold. The a priori information includes an estimate of mean and covariance of pre-measurement orthogonal polynomial sequence amplitudes associated with the surface.

主权项

1. A method of evaluating a topography of a corneal surface of an eye of a patient, the method comprising:
measuring a topography elevation field for the patient eye corneal surface; determining a measured Zernike amplitude profile for the patient eye based on the topography elevation field; combining the measured Zernike amplitude profile with a priori corneal surface information to provide an estimated Zernike amplitude profile and an estimated Zernike amplitude covariance matrix for the patient eye, the a priori corneal surface information comprising mean and covariance Zernike amplitude profiles associated with multiple corneal surfaces of a general population; constructing a corneal topography map for the patient based on the estimated Zernike amplitude profile; constructing a corneal topography uncertainty map for the patient based on the estimated Zernike covariance matrix; and evaluating the patient corneal surface topography based on the corneal topography map and the corneal uncertainty map.