Method and determination of cardiac activation from electrograms with multiple deflections

摘要

A method and system for determining activation times for electric potentials from complex electrograms to identify the location of arrhythmic sources or drivers. The method includes counting a number deflections in a recorded cardiac electrogram signal from at least one electrode for a predetermined amount of time. A deflection time is identified for each of the counted number of deflections. A most negative slope is identified between each of the identified deflections times. Each of the identified most negative slopes is correlated to a possible activation time. Each possible activation time is associated with a corresponding electrode from the at least one electrode. A spatial voltage gradient at each corresponding electrode is calculated for each possible activation time. The greatest spatial voltage gradient is identified. The greatest spatial voltage gradient is correlated to an activation time.

主权项

1. A method of determining cardiac activation times in a patient with an arrhythmia, comprising:
counting a number deflections in a recorded cardiac electrogram signal from at least one electrode for a predetermined amount of time; identifying a deflection time for each of the counted number of deflections; identifying a most negative slope between each of the identified deflections times; correlating each of the identified most negative slopes to a possible activation time; associating each possible activation time to a corresponding electrode from the at least one electrode; calculating a spatial voltage gradient at each corresponding electrode for each possible activation time; identifying the greatest spatial voltage gradient; and correlating the greatest spatial voltage gradient to an activation time.