Substituted pyrazoles

摘要

Disclosed are compounds of formula (I), wherein: X is N or R12C, Y is N or R13C, Z is N or R14C, W is SO2, C=O, CHR20 or a covalent bond; or W and R1 taken together with the 6-membered ring to which they are attached, form a moiety of formula (I)(a) or (I)(b), G is optionally substituted alkenediyl or alkanediyl, and the remaining substituents are defined herein. The compounds of formula (I) are used in the manufacture of medicaments for treating an autoimmune disease or inhibiting the progression of an autoimmune disease.