发明名称 |
Indolylmaleimide derivatives as protein kinase C inhibitors |
摘要 |
Indolylmaleimide derivatives of formula (I) comprising either a substituted phenyl, naphthyl, tetrahydronaphthyl, quinazolinyl, quinolyl, isoquinolyl or a pyrimidinyl residue are disclosed, wherein these indolylmaleimide derivatives are suitable for the treatment and/or prevention of T-cell mediated acute or chronic inflammatory diseases or disorders, autoimmune diseases, graft rejection or cancer.
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申请公布号 |
NZ525656(A) |
申请公布日期 |
2004.12.24 |
申请号 |
NZ20010525656 |
申请日期 |
2001.11.05 |
申请人 |
NOVARTIS AG |
发明人 |
ALBERT, RAINER;COOKE, NIGEL GRAHAM;COTTENS, SYLVAIN;EHRHARDT, CLAUS;EVENOU, JEAN-PIERRE;SEDRANI, RICHARD;VON MATT, PETER;WAGNER, JURGEN;ZENKE, GERHARD |
分类号 |
A61K31/404;A61K31/4178;A61K31/4439;A61K31/454;A61K31/496;A61K31/506;A61K31/517;A61K31/527;A61K31/5377;A61K31/551;A61K45/06;A61P1/04;A61P1/16;A61P3/02;A61P3/10;A61P5/14;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P21/00;A61P21/04;A61P25/00;A61P25/28;A61P27/02;A61P29/00;A61P31/18;A61P35/00;A61P37/02;A61P37/04;A61P37/06;A61P37/08;A61P43/00;C07D401/14;C07D403/04;C07D403/14;C07D471/10;C07D521/00;(IPC1-7):C07D403/04 |
主分类号 |
A61K31/404 |
代理机构 |
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代理人 |
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地址 |
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