| 摘要 |
Subject matter of the invention is an apparatus (1) for providing a sensitive volume (2) for single-sided NMR, comprising:
i) at least one first permanent magnet (3) for providing a first magnetic field at the sensitive volume (2);
ii) at least one of the following means for superimposing at least one second magnetic field for homogenizing the first magnetic field in the sensitive volume (2):
A) at least one shim magnet (5, 6, 7, 8);
B) at least one pair of shim magnets (5, 6, 7, 8); and
C) at least one electrical conductor (12, 13, 14) being connectable to an electric current source. The method and apparatus to provide a selective volume (2) according to the present invention allow the generation of highly homogeneous fields within the sensitive volume of single-sided magnets. This considerably expands the methodology available for open NMR sensors. Ex situ 1 H spectroscopy can be employed for non-invasive screening of molecular compositions, control of chemical reactions and the identification of target compounds. The most significant advantage of having high field homogeneity available for ex situ NMR is that the established techniques of multi-dimensional NMR spectroscopy and imaging can now be implemented in a straightforward way for non-destructive testing of large objects. The invention can be applied to other numbers and geometries of first permanent magnets (3) without leaving the inventive concept.
|
