发明名称 AROMATIC SIX-MEMBERED RING DERIVATIVE HAVING SUBSTITUENT AT META POSITION
摘要 PROBLEM TO BE SOLVED: To provide a compound having excellent inhibitory activity against a retinoic acid receptor-related orphan receptor γt.SOLUTION: Provided is a compound represented by a formula (I) or a pharmacologically acceptable salt thereof. [Ris a Cto Ccycloalkyl group or a phenyl group which may be substituted with 1 to 4 substituents selected from a substituent group A; Ris H, a Cto Ccarboxyalkyl group, OH, or the like; a formula -U-T- represents a formula -CH-CH- or a formula -CH=CH-; Rand Reach independently represents H, a halogen, or a Cto Calkyl group; Y represents a methylene group or O; Rrepresents a phenyl group, a pyridyl group, or the like which may be substituted with 1 to 4 substituents selected from a substituent group B; Qis N or a formula =C(R)-; Qis N or a formula =C(R)-; Rand Rare each independently H, a halogen, or the like; the substituent group A includes Cto Calkyl sulfonyl groups or the like; and the substituent group B includes a halogen, Cto Calkyl groups, a hydroxyl group, or the like.]SELECTED DRAWING: None
申请公布号 JP2016128387(A) 申请公布日期 2016.07.14
申请号 JP20150002786 申请日期 2015.01.09
申请人 DAIICHI SANKYO CO LTD 发明人 NAGAMOCHI MASATOSHI;GOTANDA TAKENORI;GOTO YASUHARU;SASAKI JUNKO;YOSHINO TOSHIJI;ISOBE TAKASHI
分类号 C07D401/12;A61K31/4184;A61K31/4439;A61K31/444;A61K31/454;A61K31/4545;A61K31/496;A61K31/506;A61K31/5377;A61P1/00;A61P1/04;A61P11/00;A61P11/06;A61P17/06;A61P19/02;A61P25/00;A61P29/00;A61P35/00;A61P37/02;A61P43/00;C07D401/14;C07D403/12;C07D405/14;C07D413/14 主分类号 C07D401/12
代理机构 代理人
主权项
地址