发明名称 A prodrug of 1,1'-(1,6-dioxo-1,6-hexanediyl)bis-d-proline
摘要 The present invention relates to the compound (2R,2'R)-bis(((((tetrahydro-2H-pyran- 4-yl)oxy)carbonyl)oxy)methyl) 1,1'-adipoylbis(pyrrolidine-2-carboxylate), pharmaceutical compositions comprising the same and the use of the same for treatment of diseases or disorders wherein depletion of serum amyloid P component (SAP) would be beneficial, including amyloidosis, Alzheimer's disease, type 2 diabetes mellitus and osteoarthritis.
申请公布号 AU2015252184(A1) 申请公布日期 2016.10.27
申请号 AU20150252184 申请日期 2015.04.27
申请人 GlaxoSmithKline Intellectual Property Development Limited 发明人 Denis, Alexis;Mirguet, Olivier;Toum, Jerome
分类号 C07D405/14;A61K31/4025;A61P25/28 主分类号 C07D405/14
代理机构 代理人
主权项
地址