发明名称 |
A prodrug of 1,1'-(1,6-dioxo-1,6-hexanediyl)bis-d-proline |
摘要 |
The present invention relates to the compound (2R,2'R)-bis(((((tetrahydro-2H-pyran- 4-yl)oxy)carbonyl)oxy)methyl) 1,1'-adipoylbis(pyrrolidine-2-carboxylate), pharmaceutical compositions comprising the same and the use of the same for treatment of diseases or disorders wherein depletion of serum amyloid P component (SAP) would be beneficial, including amyloidosis, Alzheimer's disease, type 2 diabetes mellitus and osteoarthritis. |
申请公布号 |
AU2015252184(A1) |
申请公布日期 |
2016.10.27 |
申请号 |
AU20150252184 |
申请日期 |
2015.04.27 |
申请人 |
GlaxoSmithKline Intellectual Property Development Limited |
发明人 |
Denis, Alexis;Mirguet, Olivier;Toum, Jerome |
分类号 |
C07D405/14;A61K31/4025;A61P25/28 |
主分类号 |
C07D405/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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