发明名称 PYRIDINE- AND PYRAZINE DERIVATIVES
摘要 PROBLEM TO BE SOLVED: To provide compounds that can inhibit receptor tyrosine kinases and can be applied to treatment of a variety of disorders, including cancer, septic shock, primary open angle glaucoma (POAG), hyperplasia, rheumatoid arthritis, psoriasis, atherosclerosis, retinopathy, osteoarthritis, endometriosis, chronic inflammation, and/or neurodegenerative diseases such as Alzheimer's disease.SOLUTION: The invention provides pyridine and pyrazine compounds represented by the formula (I), where X is CH or N; R is Ar or Het; Ris furyl, thienyl, pyrrolyl, imidazolyl, pyrazolyl or the like.SELECTED DRAWING: None
申请公布号 JP2016196492(A) 申请公布日期 2016.11.24
申请号 JP20160124235 申请日期 2016.06.23
申请人 MERCK PATENT GMBH 发明人 GUENTER HOELZEMANN;HANS-MICHAEL EGGENWEILER;SRINIVASA R KARRA
分类号 C07D213/82;A61K31/444;A61K31/4545;A61K31/496;A61K31/497;A61K31/501;A61K31/506;A61K31/5377;A61P9/10;A61P15/00;A61P17/06;A61P19/02;A61P25/28;A61P27/02;A61P27/06;A61P29/00;A61P31/00;A61P31/18;A61P35/00;A61P43/00;C07D401/14;C07D405/14;C07D409/14;C07D471/04;C07D491/048 主分类号 C07D213/82
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