| 发明名称 |
Oxazoline derivatives and processes for the preparation of same |
| 摘要 |
<p>Novel methods for the preparation of sidechain-bearing taxanes, comprising the preparation of an oxazoline compound, coupling the oxazoline compound with a taxane having a hydroxyl group directly bonded at C-13 thereof to form an oxazoline sidechain-bearing taxane, and opening the oxazoline ring of the oxazoline sidechain-bearing taxane so formed. Novel compounds prepared by the methods of the present invention are also provided.</p> |
| 申请公布号 |
IL121541(A) |
申请公布日期 |
2000.11.21 |
| 申请号 |
IL19930121541 |
申请日期 |
1993.12.23 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
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| 分类号 |
C07C233/17;A61K31/337;A61K31/42;A61P35/00;C07C;C07C233/30;C07C233/45;C07C233/82;C07C271/22;C07C309/66;C07C309/73;C07D;C07D263/06;C07D263/14;C07D263/16;C07D305/14;C07D307/54;C07D405/12;C07D405/14;C07D407/12;C07D409/12;C07D413/04;C07D413/12;C07D413/14;C07D417/04;C07D417/14;C07F7/18;(IPC1-7):C07D263/16 |
主分类号 |
C07C233/17 |
| 代理机构 |
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代理人 |
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