发明名称 compostos que agem nos receptores de prostaglandin múltiplo dando uma resposta anti-inflamatória geral
摘要 The present invention provides compounds, that are N-alkyl-2-(1-(5-substituted-2-(3-oxo-3-(trifluoromethylsulfonamido)propyl)benzyl)pyrrolidin-2-yl)oxazole-4-carboxamide wherein the 5 substituent is selected from the group consisting of halo and alkyloxy radicals. The compound may be represented by the following formula wherein R1 is selected from the group consisting of CO2R7 and CON(R7)SO2R7 wherein R1, R2, R3, R4, and R7 are as defined in the specification. The compounds may be administered to treat DP1, FP, EP1, EP3, TP and/or EP4 receptor mediated diseases or conditions.
申请公布号 BR112013003884(A2) 申请公布日期 2016.06.07
申请号 BR20131103884 申请日期 2011.08.19
申请人 ALLERGAN, INC 发明人 DAVID F. WOODWARD;JENNY W. WANG;JOSE L. MARTOS;JUSSI J. KANGASMETSA;WILLIAM R. CARLING
分类号 C07D413/04;A61K31/422;A61P3/00;A61P11/00;A61P19/00;A61P29/00;A61P35/00;A61P37/00 主分类号 C07D413/04
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