SULFS AS MODIFIERS OF THE BETA CATENIN PATHWAY AND METHODS OF USE
摘要
Human SULF genes are identified as modulators of the beta catenin pathway, and thus are therapeutic targets for disorders associated with defective beta catenin function. Methods for identifying modulators of beta catenin, comprising screening for agents that modulate the activity of SULF are provided.
申请公布号
WO2005017118(A2)
申请公布日期
2005.02.24
申请号
WO2004US26338
申请日期
2004.08.12
申请人
EXELIXIS, INC.;FRANCIS-LANG, HELEN;WINTER, CHRISTOPHER G.;VENTURA, RICHARD BENN ABEGANIA;HEUER, TIMOTHY S.;ZHANG, HAIGUANG
发明人
FRANCIS-LANG, HELEN;WINTER, CHRISTOPHER G.;VENTURA, RICHARD BENN ABEGANIA;HEUER, TIMOTHY S.;ZHANG, HAIGUANG
