发明名称 |
SYNTHETIC CHEMOKINE RECEPTOR LIGANDS AND METHODS OF USE THEREOF |
摘要 |
The present invention provides synthetic CXCR3 ligands, including consensus CXCR3 ligands and hybrid CXCR3 ligands; and compositions comprising the ligands. The present invention provides polynucleotides encoding the synthetic CXCR3 ligands; expression vectors comprising the polynucleotides; and host cells comprising the polynucleotidess. The present invention provides methods of treating fibrotic disorders; methods of treating angiogenic disorders; methods of treating cancer; and methods of treating bacterial infections. The methods generally involve administering to an individual in need thereof an effective amount of a subject synthetic CXCR3 ligand. |
申请公布号 |
WO2005016241(A2) |
申请公布日期 |
2005.02.24 |
申请号 |
WO2004US15357 |
申请日期 |
2004.05.13 |
申请人 |
INTERMUNE, INC.;BLATT, LAWRENCE, M. |
发明人 |
BLATT, LAWRENCE, M. |
分类号 |
A61K;A61K38/00;C07K14/52 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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