TARGETED THERAPEUTICS BASED ON ENGINEERED PROTEINS FOR TYROSINE KINASES RECEPTORS, INCLUDING IGF-IR
摘要
The present invention provides innovative proteins that bind to insulin-like growth factor-I receptor (IGF-IR), as well as other important proteins. The invention also provides innovative proteins in pharmaceutical preparations and derivatives of such proteins and the uses of same in diagnostic, research and therapeutic applications. The invention further provides cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and vectors comprising the polynucleotides encoding the innovative proteins.
申请公布号
WO2008066752(A3)
申请公布日期
2009.03.05
申请号
WO2007US24316
申请日期
2007.11.21
申请人
ADNEXUS, A BRISTOL-MEYERS SQUIBB R & D COMPANY;CAMPHAUSEN, RAY;FABRIZIO, DAVID;WRIGHT, MARTIN, C.;GAGE, PATRICK;MENDLEIN, JOHN
发明人
CAMPHAUSEN, RAY;FABRIZIO, DAVID;WRIGHT, MARTIN, C.;GAGE, PATRICK;MENDLEIN, JOHN