发明名称 |
COMPOSITIONS AND METHODS FOR ENHANCING ONCOLYTIC VIRUS EFFICACY |
摘要 |
Provided are compounds that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the cytotoxicity of virus to cells. Other uses, compositions and methods of using same are also provided. |
申请公布号 |
WO2016119052(A1) |
申请公布日期 |
2016.08.04 |
申请号 |
WO2016CA50062 |
申请日期 |
2016.01.26 |
申请人 |
OTTAWA HOSPITAL RESEARCH INSTITUTE;UNIVERSITY OF OTTAWA |
发明人 |
DIALLO, JEAN-SIMON;BODDY, CHRISTOPHER NOYCE;DORNAN, MARK;KRISHNAN, RAMYA;LE BOEUF, FABRICE;BELL, JOHN C.;MACKLIN, ANDREW;SMITH, JEFFREY |
分类号 |
A61K31/4015;A61K31/341;A61K31/36;A61K31/365;A61K31/4025;A61K31/404;A61K31/4192;A61K31/422;A61K31/4439;A61K31/4745;A61K31/50;A61K35/00;A61K35/76;C07D207/38;C07D207/40;C07D237/14;C07D307/60;C07D307/66 |
主分类号 |
A61K31/4015 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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