derivado de pirazolpirimidina ou sal medicinalmente aceitável do mesmo, composição farmacêutica, inibidor de mapkap-k2, e, agente terapêutico

摘要

A pyrazolopyrimidine derivative represented by formula (1) and pharmaceutically acceptable salt thereof exhibit excellent inhibitory activity against MAPKAP-K2. Accordingly, medicines containing this compound as an active ingredient are expected to be effective for treating diseases mediated by MAPKAP-K2 such as, for example, inflammatory disorder, autoimmune diseases, destructive osteopathy, cancer and/or tumor growth.