发明名称 TRIAZOLE AGONISTS OF THE APJ RECEPTOR
摘要 Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures where the definitions of the variables are provided herein.
申请公布号 WO2016187308(A1) 申请公布日期 2016.11.24
申请号 WO2016US33088 申请日期 2016.05.18
申请人 AMGEN INC. 发明人 CHEN, Ning;CHEN, Xiaoqi;CHEN, Yinhong;CHENG, Alan C.;CONNORS, Richard V.;DEIGNAN, Jeffrey;DRANSFIELD, Paul John;DU, Xiaohui;FU, Zice;HEATH, Julie Anne;HORNE, Daniel B.;HOUZE, Jonathan;KALLER, Matthew R.;KHAKOO, Aarif Yusuf;KOPECKY, David John;LAI, Su-Jen;MA, Zhihua;MCGEE, Lawrence R.;MEDINA, Julio C.;MIHALIC, Jeffrey T.;NISHIMURA, Nobuko;OLSON, Steven H.;PATTAROPONG, Vatee;SWAMINATH, Gayathri;WANG, Xiaodong;YANG, Kevin;YEH, Wen-Chen;DEBENEDETTO, Mikkel V.;FARRELL, Robert P.;HEDLEY, Simon J.;JUDD, Ted C.;KAYSER, Frank
分类号 C07D401/14;A61K31/4196;A61K31/4439;A61P9/00;C07D401/04;C07D413/04 主分类号 C07D401/14
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