发明名称 DRUG CONTAINING METHOTREXATE DERIVATIVE
摘要 <p>Compounds represented by general formula (I) or salts thereof, (wherein R1 represents a member selected from the group consisting of CH2, CH2CH2, CH2O, CH2S and CH2SO; R2 represents hydrogen, lower (C1-4) alkyl or benzyl; R3 represents COOR4, NHCOR5, CONR6R7, PO3H2 or SO3H; and n is an integer of from 1 to 4) which are useful as a remedy for autoimmune diseases such as systemic lupus erythematosus or nephritis such as glomerulonephritis. &lt;CHEM&gt; &lt;IMAGE&gt;</p>
申请公布号 EP0818199(A1) 申请公布日期 1998.01.14
申请号 EP19960906948 申请日期 1996.03.26
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 MIHARA, MASAHIKO
分类号 A61K31/519;A61K31/5415;C07D475/08;(IPC1-7):A61K31/505;A61P37/00;A61K31/541 主分类号 A61K31/519
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