摘要 |
The present invention relates to a chromatographic adsorbent for selectively adsorbing IgG, comprising the following formula and its corresponding enol-form, wherein X represents O, S, or NH; R<SUP>1 </SUP>represents H, C<SUB>1-6 </SUB>alkyl, C<SUB>1-6 </SUB>alkoxy, C<SUB>1-6 </SUB>alkoxy-C<SUB>1-6 </SUB>alkyl, Ar, -C(O)NHR<SUP>3</SUP>, -C(O)-R<SUP>3 </SUP>or halo; R<SUP>2 </SUP>represents H, C<SUB>1-3 </SUB>alkyl or halo; R<SUP>3 </SUP>represents H, C<SUB>1-6 </SUB>alkyl, C<SUB>1-6 </SUB>alkoxy, C<SUB>1-6 </SUB>alkoxy-C<SUB>1-6 </SUB>alkyl or Ar; n represents 0, 1, 2 or 3; Y represents a carrier. The present invention also relates to a method of producing said adsorbent as well as use thereof for separating substances by affinity chromatography.
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