发明名称 |
Use of a baculovirus to express and exogenous gene in a mammalian cell |
摘要 |
Disclosed is a method of expressing an exogenous gene in a mammalian cell, involving infecting the cell with a baculovirus whose genome carries an exogenous gene, and growing the cell under conditions such that the gene is expressed. Also disclosed is a method of treating a gene deficiency disorder in a mammal by providing to a cell a therapeutically effective amount of a baculovirus whose genome carries an exogenous gene and growing the cell under conditions such that the exogenous gene is expressed in the mammal.
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申请公布号 |
US5871986(A) |
申请公布日期 |
1999.02.16 |
申请号 |
US19940311157 |
申请日期 |
1994.09.23 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
BOYCE, FREDERICK M. |
分类号 |
A61K48/00;C12N15/866;(IPC1-7):C12N9/00;C12N15/63;C12N5/10;C07H21/04 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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