发明名称 |
PROCESS FOR PREPARING TRITYL OLMESARTAN MEDOXOMIL AND OLMESARTAN MEDOXOMIL |
摘要 |
<p>A process for the preparation of trityl olmesartan comprising (a) condens ing 4- (1-hydroxy- 1-methylethyl) -2-propyl-imidazol-5-carboxylic acid alkyl ester with trityl biphenyl bromide in the presence of a polar aprotic solve nt and a base selected from the group consisting of alkali metal carbonates, alkali metal hydroxides, alkali metal alkoxides, and tertiary amines to obt ain a compound of formula (V).</p> |
申请公布号 |
CA2663981(A1) |
申请公布日期 |
2008.04.17 |
申请号 |
CA20072663981 |
申请日期 |
2007.10.09 |
申请人 |
CIPLA LIMITED |
发明人 |
RAO, DHARMARAJ RAMACHANDRA;PUPPALA, RAVIKUMAR;KANKAN, RAJENDRA NARAYANRAO;PATHI, SRINIVAS LAXMINARAYAN |
分类号 |
C07D405/14 |
主分类号 |
C07D405/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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