发明名称 |
INDIVIDUALIZED BACTERIAL TREATMENT OF PANCREATIC CANCER |
摘要 |
An individualized bacterial treatment of cancer is provided. The treatment includes a strain of bacteria modified by in-vivo passage through tumor grafts in experimental animals, where the modified strain exhibits enhanced cancer cell-targeting of a specific malignancy arising in a unique individual to the corresponding parent strain of bacteria. The treatment uses this modified strain for the treatment human solid-tumor malignancies by inoculating an individual with a quantity of the strain; and repeating inoculations at periodic intervals where repeated inoculations tend to progressively eliminate the solid tumor malignancy in the individual. |
申请公布号 |
US2016184369(A1) |
申请公布日期 |
2016.06.30 |
申请号 |
US201615059586 |
申请日期 |
2016.03.03 |
申请人 |
AntiCancer, Inc. |
发明人 |
Zhao Ming;Uehara Fuminari |
分类号 |
A61K35/74;C12N1/36;C12N1/20 |
主分类号 |
A61K35/74 |
代理机构 |
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代理人 |
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主权项 |
1. A strain of enhanced cancer cell-targeting bacteria for individualized cancer therapy comprising:
A modified strain of bacteria, wherein said modified strain is created by at least one in-vivo passage through tumor grafts in experimental animals; and said modified strain exhibits enhanced cancer cell targeting of a specific malignancy arising in a unique individual compared to a corresponding unmodified strain of bacteria. |
地址 |
San Diego CA US |