| 摘要 |
PROBLEM TO BE SOLVED: To provide combination therapy for treating proliferative diseases.SOLUTION: The invention provides a combination therapy for treating proliferative diseases, such as cancer which comprises a first therapy comprising administration of an effective amount of taxane in a nanoparticle composition to an individual, and a second therapy comprising administration of an effective amount of at least one other agent that modifies the epigenetics in a cell. In some embodiments, the proliferative disease is resistant or unresponsive to taxane treatment when taxane is administered alone or in combination with agents other than the epigenetic modifiers.SELECTED DRAWING: Figure 1 |
