DEMAND-RELEASE BIOACTIVE COMPOSITION FOR IMPLANTABLE MEDICAL DEVICES
摘要
A biostable polymeric substrate of an implantable medical device unit includes a demand-release bioactive composition including one or more bioactive agents covalently bound to surface-modifying end groups of the substrate. Certain cellular activities, in proximity to the polymeric substrate, release substances reacting with the end groups such that the end groups release the one or more bioactive agents, which modify the certain cellular activities.
申请公布号
WO2004080339(A2)
申请公布日期
2004.09.23
申请号
WO2004US06885
申请日期
2004.03.08
申请人
MEDTRONIC INC.;STOKES, KENNETH, B.;HOBOT, CHRISTOPHER, M.;EBERT, MICHAEL, J.
发明人
STOKES, KENNETH, B.;HOBOT, CHRISTOPHER, M.;EBERT, MICHAEL, J.