MODULATION OF THE IMMUNE SYSTEM BY INOSITOL PHOSPHOLIPIDS

摘要

The invention relates to the field of immunology. More specifically, it r elates to compositions and uses thereof to suppress the immune system, among other by interference with antigen-presenting molecules and T-cell activati on. Provided is a composition for the prevention or treatment of a condition wherein suppression of T cell activation is desirable, comprising as an act ive ingredient an inositol phospholipid or a pharmaceutically acceptable sal t thereof . Said condition can be an auto-immune disease, allergic disorder or chronic inflammatory disease, for example asthma, diabetes Type I, rheuma toid arthritis (RA) or inflammatory bowel disease (IBD) . Also provided is a food item or food supplement having immunomodulating properties, comprising an effective amount of an inositol phospholipid.