STABILIZED THERAPEUTIC SMALL HELICAL ANTIVIRAL PEPTIDES

摘要

Provided are constrained peptides that inhibit HIV assembly. Pharmaceutic al compositions comprising the above peptides are also provided. Additionall y provided are methods of inhibiting replication of a capsid-containing viru s in a cell. Also provided are methods of treating a mammal infected with a capsid-containing virus. Further provided are methods of treating a mammal a t risk for infection with a capsid-containing virus. Methods of making the a bove peptides are additionally provided, as are uses of the above peptides a nd pharmaceutical compositions.