The invention provides small molecule drugs that are chemically modified by covalent attachment of a water soluble, non-peptidic oligomer. The conjugates of the invention, when administered by any of a number of administration routes, exhibits advantages over previously administered compounds.
申请公布号
WO2009042064(A3)
申请公布日期
2010.01.28
申请号
WO2008US10862
申请日期
2008.09.18
申请人
NEKTAR THERAPEUTICS;HAMMONS, AARON S.;REN, ZHONGXU;RIGGS-SAUTHIER, JENNIFER;RILEY, TIMOTHY A.;VANDERVEEN, LAURIE A.
发明人
HAMMONS, AARON S.;REN, ZHONGXU;RIGGS-SAUTHIER, JENNIFER;RILEY, TIMOTHY A.;VANDERVEEN, LAURIE A.