| 摘要 |
The present invention relates to di-pidotimod benzathine. In particular, it relates to di-pidotimod benzathine in solid form such as in crystalline or amorphous; specific polymorphs are also disclosed such as Form M, Form H and hydrate Form H of di-pidotimod benzathine. In an additional aspect of the invention, solvates and cocrystals of hydrate Form H di-pidotimod benzathine are provided. In further aspects of the invention, processes for making solid di-pidotimod benzathine, crystalline di-pidotimod benzathine, amorphous di-pidotimod benzathine, Form M di-pidotimod benzathine, hydrate Form H di-pidotimod benzathine and Form H di-pidotimod benzathine are provided. In additional aspects of the invention, methods of treating infections or inflammatory diseases using one or more of di-pidotimod benzathine, solid di- pidotimod benzathine, crystalline di-pidotimod benzathine; amorphous di- pidotimod benzathine, Form M di-pidotimod benzathine, Form H di-pidotimod benzathine or solvates, cocrystals or hydrates thereof are provided. |
