发明名称 |
CHROMENONE INHIBITORS OF MONOCARBOXYLATE TRANSPORTERS |
摘要 |
The invention provides compounds effective as inhibitors of monocarboxylate transporters such as MCT1 and MCT4, which can be used for treatment of medical conditions wherein treatment of the condition with a compound having an inhibitor effect on MCT1, MCT4, or both is medically indicated. Compounds of the invention can have antitumor, antidiabetes, anti-inflammatory, or immunosuppressive pharmacological effects, and can be effective for treatment of cancer and of type II diabetes. |
申请公布号 |
WO2016118822(A1) |
申请公布日期 |
2016.07.28 |
申请号 |
WO2016US14455 |
申请日期 |
2016.01.22 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
BANNISTER, THOMAS, D.;WANG, HUI;WANG, CHAO;CLEVELAND, JOHN, L. |
分类号 |
A61K31/277;A61K31/5377;C07D311/22 |
主分类号 |
A61K31/277 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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