| 发明名称 |
THERAPEUTIC APPROACHES FOR TREATING PARKINSON'S DISEASE |
| 摘要 |
The present invention relates to compositions and methods for the treatment of Parkinson's disease and related disorders. More specifically, the present invention relates to novel combinatorial therapies of Parkinson's disease and related disorders targeting the alpha-synuclein aggregation network. In particular, the invention relates to compounds which, alone or in combination(s), can effectively protect neuronal cells from alpha-synuclein aggregates. The invention also relates to methods of producing a drug or a drug combination for treating Parkinson's disease and to methods of treating Parkinson's disease or a related disorder. |
| 申请公布号 |
US2016193163(A1) |
申请公布日期 |
2016.07.07 |
| 申请号 |
US201615011900 |
申请日期 |
2016.02.01 |
| 申请人 |
PHARNEXT |
发明人 |
COHEN DANIEL;NABIROCHKIN SERGUEI;CHUMAKOV ILYA;HAJJ RODOLPHE |
| 分类号 |
A61K31/185;A61K31/197;A61K9/00;A61K31/137 |
主分类号 |
A61K31/185 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating Parkinsonism in a subject in need thereof, comprising administering to said subject an effective amount of cinacalcet and acamprosate, or prodrugs or salt(s) or derivative(s) of any chemical purity, or sustained release formulation(s) thereof. |
| 地址 |
ISSY LES MOULINEAUX FR |
