Antibody binding microbial heparin binding motif to retard or prevent microbial biofilm formation on implanted medical devices

摘要

Methods and reagents for ameliorating biofilm formation on a surface of an indwelling or implanted device in a patient resulting in decreased virulence of microorganisms such as Candida species and/or Staphylococcus species.

主权项

1. A composition comprising at least one biocompatible excipient and an antibody capable of binding to peptide HKQEKQKKHQIHKV (SEQ ID NO: 4) wherein the excipient comprises a Tris buffer and wherein the antibody is a non-human humanized antibody.